Antitubercular Drugs. Antisyphilitic Drugs

Date: 2015-10-07; view: 649.

1. A 35-year-old man under the treatment for pulmonary tuberculosis has acute pain onset of right big toe, swelling, and low-grade fever. The gouty arthritis was diagnosed and high serum uric acid level was found. Which of the following antituberculosis drugs are known for causing high uric acid levels?

*A. Pyrasinamide

B. Aminosalycylic acid

C. Rifampicin

D. Thioacetazone

E. Cycloserine

2. The patient has appealed to the doctor with complaints to red color of urine and tears. It is known, that he is treated from pulmonary tuberculosis. What drug can cause this adverse effect?

*A. Rifampicin

B. Isoniazid

C. Metronidazole

D. Streptomycin sulfate

E. Doxicicline

3. The first-line drug for treatment of tuberculosis is prescribed to 38-year-old patient. It is known that drug causes several adverse effects, which are connected with oppressing of formation of pyridoxal-phosphate. Call this drug.

*A. Isoniazid

B. Rifampicin

C. Doxicicline

D. Metronidazole

E. Chingaminum

4. The neuritis of optic nerve occurred in patient in result of treating with certain antituberculosis drug. Identify this drug.

*A. Isoniazid

B. Ethambutol

C. Kanamycin

D. Rifampicin

E. Streptomycin

5. It is known, that patient A. with pulmonary tuberculosis has hereditary insufficiency of N-acetyltransferase. Indicate the antituberculosis agent which can promote the development of marked toxic effects in this patient.

*A. Isoniazid

B. Streptomycin

C. Ethambutol

D. Rifampicin

E. Sodium salt of PAS

6. In clinical practice tuberculosis is treated with izoniazid – that is an antivitamin able to penetrate into the tuberculosis bacillus. Tuberculostatic effect is induced by the interference with replication processes and oxidation-reduction reactions due to the buildup of pseudo-coenzyme:

*A. NAD

B. TDP

C. FMN

D. CoQ

E. FAD

7. A patient suffering from syphilis has been treated with bismuth preparations. As a result of it some grey spots turned up on the mucous membrane of the oral cavity; nephropathy symptoms were also present. What drug should be used for treatment of bismuth intoxication?

*A. Unithiol

B. Naloxone

C. Bemegride

D. Nalorphine

E. Methylene blue