INDEPENDENT WORK of the STUDENTS

Date: 2015-10-07; view: 456.

THEORETICAL QUESTIONS NECESSARY FOR ACHIEVING of the PRACTICAL CLASSES

ORGANIZATIONAL STRUCTURE of the PRACTICAL STUDY

1. Definition and Categorization (classification) of hereditary diseases.

2. Chromosome diseases are caused by changing of number and shape of autosome chromosomes.

3. Chromosome diseases are caused by changing of sex chromosomes' number.

4. Gene diseases (molecular diseases). Plural congenital disorders of ontogenesis.

5. Gene diseases. Diseases of metabolism disorders.

6. Multifactorial disorders.

7. Prevention of the hereditary diseases.

To acquisition of practical skills of using the genetic laws and methods of examination solve tasks.

1. Build the pedigree. Proband is woman having schizophrenia. Proband's father, brother and sister are healthy. Relatives of proband's father are following: brother has schizophrenia and two sisters are healthy. Father and mother of proband's father (proband's grandfather and grandmother) are healthy, but sister of grandmother is sick. Proband's mother of, grandfather and grandmother from mother's side are healthy. Analyze the family tree to define the type of inheritance, the genotypes of members of family tree, and prognosis of birthing of sick children.

2. Build the pedigree. Proband is man having cataracta. His mother and mother's mother (proband's grandfather) have the cataracta too. Uncle and aunt from of proband from mother's side are healthy. Proband's father, aunt from side of father, grandmother and grandfather from side are healthy. Wife of proband, her sisters, and two her brothers, and her parents are healthy. Proband has two children: son is sick and daughter is healthy. Analyze the family tree to define the type of inheritance, the genotypes of members of family tree, and prognosis of birthing of sick children.

3. Build the pedigree. Proband is man having Duchenne Muscular Dystrophy. His mother, mother's mother (proband's grandmother), and grandfather are healthy. Mother's sister is healthy too, but mother's brother is sick. Proband's father, aunt from side of father, grandmother and grandfather are healthy. Analyze the family tree to define the type of inheritance, the genotypes of members of family tree, and prognosis of birthing of sick children.

4. Build the pedigree. Proband is healthy man. His sister, father and grandmother have vitamin – D – firm rickets. Father's sister has rickets too. Proband's mother, two her sisters, mother (proband's grandmother), and father (proband's grandfather) are healthy. Analyze the family tree to define the type of inheritance, the genotypes of members of family tree, and prognosis of birthing of sick children.

5. Build the pedigree. Proband is man having hypertrichosis of auricle. His brother, father, uncle (father's brother) and grandfather have hypertrichosis too. Proband's sister, mother, aunt (mother's sister), grandmother (mother's mother) and grandfather (father's father) are healthy. Analyze the family tree to define the type of inheritance, the genotypes of members of family tree, and prognosis of birthing of sick children.